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Louis Sanford Goodman (August 27, 1906 – November 19, 2000) was an American pharmacologist. He is best known for his collaborations with Alfred Gilman, Sr., with whom he authored the popular textbook ''The Pharmacological Basis of Therapeutics'' in 1941 and pioneered the first chemotherapy trials using nitrogen mustard. ==Life and career== Goodman was born in Portland, Oregon in 1906 and received his B.A. from Reed College in 1928 and an M.D. from the University of Oregon Medical School in 1932. After interning at Johns Hopkins Hospital, he joined the Yale School of Medicine faculty, where he met Alfred Gilman. They began teaching pharmacology courses together and began to develop a textbook, which was published as ''The Pharmacological Basis of Therapeutics'' in 1941. While at Yale, Goodman and Gilman were assigned a government contract in nitrogen mustard research in 1942. With knowledge that the compound depleted white blood cells, the pharmacologists experimented with intravenous injections on a terminally ill lymphosarcoma patient in Gustaf Lindskog's care. Though the tumor regenerated and killed the patient, the drug's success in briefly eliminating the tumor is considered a historic accomplishment in chemotherapy treatment, and the compound is still used as a chemotheraputic agent.〔 Goodwin was appointed an assistant professor at the University of Vermont in 1937, and became its chair of pharmacology and physiology in 1943.〔〔(【引用サイトリンク】url=http://www.nasonline.org/member-directory/deceased-members/20001397.html )〕 Then, in 1944, he moved to Salt Lake City to found a department of pharmacology at the University of Utah College of Medicine.〔 There, Goodman demonstrated that the paralysis induced by curare were temporary, which he did by injecting a colleague with the relaxant.〔 Goodman retired in 1971 and remained in Salt Lake City for the remainder of his life, continuing to teach at the College of Medicine. He died on November 19, 2000, at the age of 94.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Louis S. Goodman」の詳細全文を読む スポンサード リンク
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